2022 Collaborative Patient-Centered Research Update: Peer-Pal Intervention (PPI)

April 30, 2025

Dr. Tze-Woei Tan and Dr. Emily Rosario, were awarded the 2022 Collaborative Patient-Centered Research (CPCR) grant for their project, Implementing Peer-Pal Intervention (PPI) in Low-income Patients with Ischemic Diabetic Foot Ulceration (DFU), by the Foundation to Advance Vascular Cures.

The Peer-Pal Support Intervention (PPI) program introduces an equity-focused peer-driven care model to diabetic foot ulceration (DFU), designed to improve health outcomes for low-income patients at high risk of diabetes-related amputations. DFUs disproportionately affect minority and economically disadvantaged populations, often leading to serious complications due to barriers in accessing proper wound care. To address these challenges, the PPI program introduces a patient-centered, culturally tailored intervention that connects newly diagnosed patients with Peer-Pals—individuals who have successfully managed DFUs themselves. These mentors provide emotional support, treatment adherence guidance, and assistance in navigating the healthcare system.

Since its launch in July 2023, the program has reached several key milestones. The program successfully trained five Peer-Pals, equipping them with the knowledge to mentor newly diagnosed DFU patients. Additionally, the study has enrolled 18 individuals from Casa Colina Hospital and Centers for Healthcare, Rancho Los Amigos National Rehabilitation Center, and the University of Southern California. A Community Advisory Board (CAB) was established, bringing together a diverse 12-member panel that includes patients, caregivers, healthcare professionals, and industry representatives. Meanwhile, ongoing data collection and analysis is providing critical insights into how peer support influences self-care confidence, healthcare navigation, and quality of life for patients.

Early results show that participants report increased confidence in managing their condition, improved treatment adherence, and overall better quality of life. The project’s findings were recently presented at the 20th Annual Academic Surgical Congress in February 2025. Encouraged by these outcomes, the team now aims to start a larger clinical trial to further validate the impact of the Peer-Pal model. By integrating peer mentorship into diabetic foot care, this initiative has the potential to reduce amputation rates and transform long-term patient outcomes. The Foundation to Advance Vascular Cures remains committed to supporting projects like these that advance patient-centered solutions and support for vascular health. 

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To learn more about Vascular Cures’ Patients as Partners Program, please visit: https://vascularcures.org/patients-as-partners/